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Showing posts with label mouse. Show all posts
Showing posts with label mouse. Show all posts

11.4.11

Salman Rushdie about Chernobyl

Dear michael,
Finally, I gave the talk about my MSc thesis today here in the institute, and as you expected, people were much more interested to discuss the implications of the Fukushima accident (which of course also has to do with radio-iodine) than the genetic studies I did last year in Munich. I doubt if people could really estimate what we found out with you doing the genetic studies in mice.
Before giving the talk to my colleagues, I practised a bid at home and did the same presentation at home to my family. My parents were much more interested in the 1986 Chernobyl disaster, which I used as introduction to explaine the importance of the radio-iodine incorporation studies. I now understand why: When the Chernobyl disaster happened, I was exactly 10 month old, so according to all the studies that I read for my thesis, I was at the most sensitive age when the radioactive cloud reached Sweden. You see how differently people anticipate events: Nowadays everybody is worried about the Fukushima disaster from 3 weeks ago, whereas my parents are obviously still worried if their daughter might have been affected by the Chernobyl fall-out.
My dad, who is always very interested in names and their meaning wanted to know what this "Chernobyl" means. But my mom immediately shouted "Who cares about names, if the only daughter we have might have been irradiated". Thanks god I could relieve her anxiety by showing the graphs from my thesis about the latency time of thyroid-cancer, and she understoud that the danger is already very low for me cause I"m old enough ("Eh Vay, old enough for what? Who can tell me"). Now, Mom could lean back again and Dad came back to his question about the meaning of "Chernobyl". I still remembered that you once told me it is the russian and ukrainian word for Artemesia, a shrub used as herb for cooking and in traditional chinese medicine. Since dad is not so specialized in botanics, he looked it up in his precious Encyclopedia Iranica and found something interesting: Artemisia (or Wormwood) is called in turkish Shaybani, and this was also the name of an invader that came in the 16th century from middle asia (Usbekistan, where you got your Polou-recipie from) to Iran. His persian name was شیبک خان ازبک
and he defeated Barbur, the first ruler of the Moguln-empire. Since the persian Shah Ismail began to fear that Shaybani might look for other neighboured countries to conquer, he attacked him in the battle of Marv. Shaybani was killed in this battle and parts of his body send by Shah Ismail to other leaders of neighboured empires as a warning.
My Dad told us all these stories of wars, victories and defeates with great passion. But Mom and myself as usual questioned the meaning of this for the progress of civilization and for the goal of human happiness. We suspected that in all these heroic stories of the battles between nations and empires, the million tears and lost lives were forgotten. Neither my Dad nor the encyclopedia iranica knew anything about the families of Shaybani, Emir of Buchara, of Barbur, the first Moguln ruler or of Shah Ismail of Persia. During these persistent fights to expand their empires or to defend it against the attacks from enemies, they were virtually rarely at home. Who were looking after their wives and children ? If today a husband and father would be absent from home so frequently, I guess the department for child care or some family judges would fine hime.

Hope you don"t have these problems, and even though you spend much time in the lab and at scientific meetings, your family does not feel neglected.
Hope you are doing fine, Take Care
/ghazal

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Ghazal my Dear,

I think I am not as bad as the military leaders of these historical times you describe in your mail. At least I always stay in contact with home, using mobile phone or skype ;-)

The history of the rise and fall of the persian empire in the 16th century, its defeat by the ottoman empire in the west and its link with the rise of the Moguln empire in the east is the background of Salman Rushdie"s novel "The Enchanting Florentine". If you read it, you will be able to tell your dad the more private side of Shaybani, Barbur and Shah Ismail, because in this novel Rushie introduces a "lost" sister of Barbur. Her name is Qara Köz (or "black eyes") , and she first becomes wife of Shaybani, than of Shah Ismail and finally of the ottoman general Argul, who is originally italianian and defeats Shah Ismail. The novel uses this magic realismen to show how a young, beautiful woman always changes from one winning horse to the next. But it also shows the price she has to pay for it, that she never really builds a home for herself and never raises children. This at least is the state on page 367, and there are another 108 to come. Maybe I read them tonight, maybe there will be an happy end for her.

In case there wont be a happy end for Qara Köz, do you want me to tell you the rest of the novel ?
Hope you have a nice evening, enjoy the spring, relax and don"t use your brother automatic e-mail-response program to send me an answer.

Take Care, my Dear
Michael

2.1.11

The genealogy of mice (part 2)

Hi michael,
While searching for a paper that Matts recommended me to read about UV-repair, I found an article reporting a new study about the migration of house-mice throughout europe during the last 10 000 years. I remember you once wrote me a story about the colonialization of europe by the two mouse species M.musculus musculus (eastern-mouse) and M.musculus domesticus (western-mouse). Interestingly, this new paper shows that the western house-mouse travelled like a blind passenger together with the civilisations that managed to grow and store grains. And this started (you guess it) in Iran (and probably further east on the indian sub-continent).



So you see, whithout the ancient agricultural developments in Iran, the progress in experimental genetics (including my MSc-project !!) which is so much based on M.musculus domesticus would not be possible. House-mice were known in Iran already 13 000 years ago. They arrived in Germany (including Neuherberg) only 3 000 years ago. Do you know, if the two strains that I studied in my MSc project  (the albino FVB and the spotted JF1) belong to M.musculus domesticus ?  Would be so nice for me to know, whether they are also descendents from the iranian mouse population.
Enjoy the winter time
TAKE CArE
/ghazal

PS: If you write about going-swimming these days, I assume you discovered a hot spring somewhere around Munich ?


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Hi Ghazal, I very much admire that you spend some of the holidays to learn for your PhD project and - what is even more unusual - that you still find something exciting related to your MSc project (like the mouse colonialization paper that you mention above). It is interesting, indeed, not just from a genetics point of view, but also considering the house-mouse as a companion to the civilized men, that populated the world together. Have you seen the dotted line on the map, that runs north to south across europe ? This line as I wrote before separates the western mouse (M.m.domesticus) from the eastern mouse (M.m.musculus) world. We believe, it coincides with the cold-war demarcation line between the "socialist" eastern-europe and the "free" western-europe. How this co-incidence happened, nobody knows. Obviously, the mice were there much earlier (according to the study at iron-age), wheres human did the east-west-separation just 60 years ago (and it lasted only for 40 years).
The separation line between M.m.domesticus and M.m.musculus runs also along the Isar-river here in Munich. So during your staying in Unterschleissheim, you have been surrounded by the house-mouse, which as you mentioned above originated from Persia. What is a pitty, I think, that in Stockholm you are clearly east of the separation line, i.e. you now live in the world of M.m.musculus, which originated from central Asia (I guess mongolia).
These mice are known to be much more wild in their behaviour, unlike the FVB or JF1
that you worked with in your MSc project. Therefore, if you meet one in your house in Sweden or in the field, be careful. They wont let you do tail-clipping, ear-marking or measuring incorporated Iodine-activity as you did in your MSc project. They tend to have a much stronger self-defence instinct than FVB or JF1. Both are, by the way not pure M.m.domesticus strains. FVB/N is a laboratory inbred strain derived from hybrids between M.m.domesticus and M.m.musculus and contains alleles from both. JF1 was bred in Japan by fancy breeders (just as a hobby) and goes back to the mixed line of M. molossinus, which developed my matings of M.m.muscullus and M.m.castaneous.
Hope you are fine, Ghazal

Take Care, Michael

PS: I have not discovered a hot spring here in Munich. Therefore, I go for swimming in the little river next to our house. But it has a constant temperature of 8 degrees celsius, which as compared to the outside -10 degrees appeares quite warm.

26.5.10

The mouse adores the persian cat

Ghazal, you are to much a goddess to be conquered by a ordinary guy like your boy-friend, who is doing body-building and dreams of a life as manager. You should not be touched by a human beeing, and I would never consider touching you. I might touch you with my eyes, but only to adore you. Your magic stays in an immaterial sphere. I do not know how much of this magic is just a projection of hidden dreams, that by chance were caught by a student sitting in the first row with an expression on her face, as if the blue colour of your eyes merely reflected your thinking about the moon and the blue, blue sea. What would have happend, if I would have given you a slight kick with the finger, just as to wake somebody up who had fallen asleep? Would you come back to this world with your dreams burst into pieces of coloured glass ? (26-05-2010)